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Want to keep track of the largest startup funding deals in 2026 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The 小蓝视频色情网页版 Megadeals Board.

This is a weekly feature that runs down the week鈥檚 top 10 announced funding rounds in the U.S. Check out last week鈥檚 biggest funding deal roundup here.

Another week, another bevy of big rounds. For this past week, the largest round was a reported $5 billion -backed financing for foundational AI unicorn , followed by a $1 billion investment in . Other sizable rounds went to companies in sectors including energy storage, health testing, nuclear power, fintech, and, yes, AI.

1.听, $5B, foundational AI: AI lab Safe Superintelligence announced a long-term with Nvidia to rapidly accelerate its growth. The deal included a $5 billion investment from the chip giant with an eye toward boosting compute resources for Safe Superintelligence, a Silicon Valley startup founded by co-founder .听

2.听, $1 billion, fusion energy: Commonwealth Fusion Systems, a startup working on fusion energy technology and developing a grid-scale fusion power plant, raised $1 billion in fresh funding from unspecified investors. The round brings the total invested to date for the Massachusetts-based company to $4 billion.

3.听, $550M, thermal energy storage: Antora Energy, a company that provides energy through thermal batteries to data centers, announced that it has closed on $550 million in a Series C funding round. and co-led the financing for the nine-year-old, San Jose-based company.

4.听, $450M, health testing: Austin-based Function, a provider of lab testing, imaging, and personal health information that markets to consumers, secured $450 million in growth financing from .听

5.听, $370M, nuclear energy: Antares, a nuclear fission energy company that develops compact microreactors for defense and space applications, raised $370 million in Series C equity funding. and led the financing for the three-year-old company, which raised $100 million in debt funding alongside the equity investment.听

6.听, $200M, AI simulation: Simile, a developer of AI tools for running simulations, said it picked up over $200 million in fresh funding at a $2 billion post-money valuation. led the round, which comes just five months after the Palo Alto-based company launched its product.

7.听, $190M, cybersecurity: Cybersecurity provider ThreatLocker closed on $190 million in Series F funding to hone its platform and expand internationally. led the round for the Orlando-based company.

8.听, $170M, fintech: New York-based CAIS, an alternative investment platform for independent financial advisors, secured $170 million in Series D financing. led the round, which set a valuation for the company of more than $2 billion.

9.听, $160M, fintech: PEX, an AI-enabled provider of prepaid and charge cards for businesses, along with tools to track finances, raised $160 in equity and debt funding, with as lead investor.

10.听, $145M, AI infrastructure: Eliyan, a developer of connectivity technology for AI infrastructure, completed its Series C with a total of $145 million at a $1 billion valuation. led the financing for the five-year-old Santa Clara, California-based company.

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